Thorn and Paw starts out tough in that the central room is close enough to the exit that Dimension Door back doesn't break lock on the mini-bosses and major reapers. I did it with no equipment and using the resurrection shrine to resurrect, shoot Meteor Swarm, die then repeat. And then I had to do it again once the north door is opened and you have to kill two mini-boss bears. That was most of my deaths, probably another six to ten doing the run.

For the most part the monsters are easy. Slow and easy to kill. The vine guys shoot but plenty of walls and corners to hide behind. The red zombies come at you faster but again one or two shadow blade hits kills them. The wolves are annoying because they're fast and hiding. Sometimes though a reaper would spawn with them so hit the reaper with meteor swarm a couple of times kills all the wolves. Fair sized rooms and big hallways with good sight lines favors me.

A fair number of reapers. I actually fought three major reapers (one at a time and not doom reaper) in the first big room running around and somehow avoiding getting hit. I'm level 29 now and with equipment upgrades I can meteor swarm and kill a vengeance or despair reaper in like four or five hits so just have to stay alive for half a minute.

Total Time: 4-1/2 hours. Deaths: 37.